WNK1 Archives - Shiwarski Tissue Engineering Lab

Kidney-specific WNK1 amplifies kidney tubule responsiveness to potassium via WNK body condensates

Boyd-Shiwarski CR, Beacham RT, Griffiths SE, Shiwarski DJ, Knoell SA, Nkashama LJ, Querry K, Marcizsyn AL, Huang CL, Stocker SD, Subramanya AR. JCI (2025)

Cell Biology Review WNK1

A New Phase for WNK Kinase Signaling Complexes as Biomolecular Condensates

Boyd-Shiwarski CR, Shiwarski DJ, Subramanya AR. Physiology (2024)

Cell Biology Imaging WNK1

WNK Kinases sense molecular crowding and rescue cell volume via phase separation

Boyd-Shiwarski CR*, Shiwarski DJ*, Griffiths SE, Beacham RT, Norrell L, Morrison DE, Wang J, Mann J, Tennant W, Anderson EN, Franks J, Calderon M, Connolly KA, Weaver CJ, Weckerly CC, Pandey UB, Donnelly CJ, Sun D, Rodan AR, Subramanya AR. Cell (2022) *Equal Contributions

Cell Biology WNK1

Effects of extreme potassium stress on blood pressure and renal tubular sodium transport

Boyd-Shiwarski CR, Weaver C, Beacham R, Shiwarski DJ, Connolly K, Nkashama L, Mutchler S, Griffiths S, Knoell S, Marciszyn A, Subramanya AR. AJP Renal (2020) PMID: 32281415

Cell Biology WNK1

Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent

Boyd-Shiwarski CR, Shiwarski DJ, Roy A, Namboodiri HN, Nkashama LJ, Xie J, McClain KL, Marciszyn A, Kleyman TR, Tan RJ, Stolz DB, Puthenveedu MA, Huang CL, Subramanya AR. Mol Biol Cell. 2018 Feb 15;29(4):499-509. PMID: 29237822; PubMed Central PMCID: PMC6014176.

WNK1

Kidney-specific WNK1 amplifies kidney tubule responsiveness to potassium via WNK body condensates

A New Phase for WNK Kinase Signaling Complexes as Biomolecular Condensates

WNK Kinases sense molecular crowding and rescue cell volume via phase separation

Effects of extreme potassium stress on blood pressure and renal tubular sodium transport

Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent

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