Press Coverage
Combining engineering principles
& fundamental biology to advance
regenerative medicine
& fundamental biology to advance
regenerative medicine
Areas of Research
Working to engineer non-animal model systems to study human development and disease.
Translational Medicine
Vascular Disease, Pulmonary Hypertension, Kidney Disease, Thrombosis
Tissue Engineering
3D Bioprinting, Microfluidics, Stem cells, Organoids, and TEBVs
Cell Biology
GPCRs, Receptor Trafficking, Molecular Condensates, Phase Separation, Live Cell Imaging
Open-Source Design
3D Bioprinters, Biaxial Stretchers, Alignment systems, Myography
STEL Research Highlights
Recent publications and highlighted work from our lab
Press Coverage
Press Coverage
Press Coverage
Scientific
Press Coverage
HIGHLIGHTCollagen-based High Resolution Internally Perfusable Scaffolds (CHIPS)
We implemented a multi-material bioprinting approach to control 3D spatial patterning, ECM composition, cellularization, and material properties to create a glucose-responsive, insulin-secreting pancreatic-like CHIPS with VE-cadherin+ vascular-like networks. - Science Advances - 2025
Daniel Shiwarski, Ph.D.
Principle Investigator
Principle Investigator
HIGHLIGHTHemoLens as an open-source 3D printed pressure myography system
Vessel myography systems are expensive preventing high throughput screening. We developed a flexible open source myograph to studying the mechanical properties of tissue engineered blood vessels (TEBVs) with integrated imaging system and micropositioning system costing less than $750 (3% the cost of commercial systems). Publication just out in Device!
Antonio Tavares & Liam Aranda-Michel
Students
Students
Areas of Focus and Education
Building community and inclusivity through open-source engineering design
An Open-source Community
for Bioengineering
Why Open
Source?
Building Bioprinters
Using open-source motion control boards running Duet3D or Klipper firmware and off the shelf 3D printer components we are able to lower the barrier to entry for research labs to gain access to additive manufacturing for biomedical applications.
Benefits of Open-source Applications in Bioengineering
Lowering Cost
Fast Iteration
Labs Trained
Our Funding Partners
Shiwarski Tissue Engineering Lab
University of Pittsburgh
Bioengineering and Medicine
Vascular Medicine Institute
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