A New Phase for WNK Kinase Signaling Complexes as Biomolecular Condensates
Boyd-Shiwarski CR, Shiwarski DJ, Subramanya AR. Physiology (2024)
WNK Kinases sense molecular crowding and rescue cell volume via phase separation
Boyd-Shiwarski CR*, Shiwarski DJ*, Griffiths SE, Beacham RT, Norrell L, Morrison DE, Wang J, Mann J, Tennant W, Anderson EN, Franks J, Calderon M, Connolly KA, Weaver CJ, Weckerly CC, Pandey UB, Donnelly CJ, Sun D, Rodan AR, Subramanya AR. Cell (2022) *Equal Contributions
Effects of extreme potassium stress on blood pressure and renal tubular sodium transport
Boyd-Shiwarski CR, Weaver C, Beacham R, Shiwarski DJ, Connolly K, Nkashama L, Mutchler S, Griffiths S, Knoell S, Marciszyn A, Subramanya AR. AJP Renal (2020) PMID: 32281415
Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent
Boyd-Shiwarski CR, Shiwarski DJ, Roy A, Namboodiri HN, Nkashama LJ, Xie J, McClain KL, Marciszyn A, Kleyman TR, Tan RJ, Stolz DB, Puthenveedu MA, Huang CL, Subramanya AR. Mol Biol Cell. 2018 Feb 15;29(4):499-509. PMID: 29237822; PubMed Central PMCID: PMC6014176.
Shiwarski Tissue Engineering Lab
University of Pittsburgh
Bioengineering and Medicine
Vascular Medicine Institute
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